ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections

Kelly CR, Fischer M, Allegretti JR, LaPlante K, Stewart DB, Limketkai BN, Stollman NH. Kelly CR, et al. Am J Gastroenterol. 2022 Feb 1;117(2):358. doi: 10.14309/ajg.0000000000001529. Am J Gastroenterol. 2022. PMID: 34658366 No abstract available.

Abstract

Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios.

Comment in

McFarland LV, Kullar R, Johnson S, Sniffen JC, Woolard K, Goldstein EJC. McFarland LV, et al. Am J Gastroenterol. 2022 Mar 1;117(3):501. doi: 10.14309/ajg.0000000000001567. Am J Gastroenterol. 2022. PMID: 35020606 Free PMC article. No abstract available.

Kelly CR, Fischer M, Allegretti JR, LaPlante K, Stewart DB, Limketkai BN, Stollman N. Kelly CR, et al. Am J Gastroenterol. 2022 Mar 1;117(3):501-502. doi: 10.14309/ajg.0000000000001638. Am J Gastroenterol. 2022. PMID: 35137698 No abstract available.

Clemens JQ. Clemens JQ. J Urol. 2023 Feb;209(2):428-429. doi: 10.1097/JU.0000000000003041. Epub 2022 Nov 3. J Urol. 2023. PMID: 36326582 No abstract available.

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